Should you have a Neurology/Stroke related professional resource that you would like to display, please contact GNYMASCC with the details at the email listed below.
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Activase® (alteplase) Therapy Card with NIH Stroke Scale
Activase® Clinical Profile Brochure
Dosing and Administration of Activase® DVD
Activase® Patient Discussion Guide
NIH Stroke Scale Testing Card (English)
High Blood Pressure: It May Be Riskier Than You Think
Know Stroke. Know the Signs. Act in Time.
English & Spanish
Stroke Risk Factors and Symptoms
English & Spanish
What You Need to Know About Stroke
Know Stroke Information Card
Stroke: Challenges, Progress, and Promise
Stroke: Hope Through Research
English & Spanish
Post-Stroke Rehabilitation
English & Spanish
Brain Basics: Preventing Stroke
CLICK link below for articles
2021 Guideline for the Prevention of Stroke in Patients With Stroke and Transient Ischemic Attack
Care of the Patient With Acute Ischemic Stroke (Prehospital and Acute Phase of Care)
Care of the Patient With Acute Ischemic Stroke (Posthyperacute and Prehospital Discharge)
Clinical Practice Guidelines for Stroke
Guidelines for the Early Management of Patients With Acute Ischemic Stroke: 2019 Update to the 2018 Guidelines for the Early Management of Acute Ischemic Stroke: A Guideline for Healthcare Professionals From the American Heart Association/American Stroke Association
https://www.ahajournals.org/doi/10.1161/STR.0000000000000211
Guidelines for the Management of Spontaneous Intracerebral Hemorrhage
https://www.ahajournals.org/lookup/doi/10.1161/STR.0000000000000069
Guidelines for Adult Stroke Rehabilitation and Recovery
Comprehensive Overview of Nursing and Interdisciplinary Care of the Acute Ischemic Stroke Patient
https://ahajournals.org/doi/10.1161/STROKEAHA.109.192362
Benefits of tPA for Stroke Extended to 9 Hours Post Onset
https://www.medpagetoday.com/neurology/strokes/79734
Like mechanical revascularization, IV thrombolysis with a pharmacologic agent can help preserve the functional capabilities of patients even 4.5 to 9 hours after stroke onset -- provided they still have salvageable brain tissue, published data from the EXTEND trial showed.
People who presented late but with imaging results showing relatively small infarct cores still had better odds of good functional outcomes after getting alteplase, as 35.4% of this group scored a 0 or a 1 on the modified Rankin scale (mRS) at 90 days, compared with 29.5% of the placebo arm (adjusted RR 1.44, 95% CI 1.01-2.06), reported Geoffrey Donnan, MD, of Royal Melbourne Hospital, and colleagues in the New England Journal of
Medicine. The trial randomized 225 stroke patients who had arrived at the hospital later than the first 4.5 hours after symptom onset or after waking up with a stroke. They were imaged with CT perfusion imaging and perfusion-diffusion MRI.
Main results from EXTEND were first presented in February at the American Heart Association's International Stroke Conference.
Yet a secondary ordinal analysis of the distribution of mRS scores did not show better functional improvement at 90 days with late thrombolysis, according to the full New England Journal paper, which also came with an accompanying editorial.
In addition, the risk of symptomatic intracerebral hemorrhage was increased with alteplase (6.2% vs 0.9%, adjusted RR 7.22, 95% CI 0.97-53.5).
"The authors are to be commended for a groundbreaking trial. It suggests, for the first time, that the benefit of alteplase may persist after more than 4.5 hours of symptoms in selected patients," Pooja Khatri, MD, MSc, of the University of Cincinnati, told MedPage Today.